Saturday, December 27, 2025

Forget Moderna Stock, This is a Much Better Buy

Investors flocked to Moderna (NASDAQ: MRNA) stock in the early days of the pandemic for one big reason: The company sold one of the world’s most-needed products, a coronavirus vaccine. The vaccine brought in billions of dollars of revenue, and with this first product, Moderna went from a clinical-stage biotech to a highly profitable commercial-stage company in a matter of months.

Though Moderna stock soared back then, in more recent times, the stock has stumbled. The company has seen vaccine sales decline, and its second big product — its respiratory syncytial virus (RSV) vaccine — hasn’t performed as well as expected when it comes to delivering growth. Still, Moderna has made progress on cost cuts and has refocused its pipeline on several promising programs. And investors may be taking notice. The stock has climbed more than 30% over the past month.

But, if you’re looking to invest in a surefire biotech winner, forget Moderna stock. The following player is a much better buy…

Two researchers study something on a tablet in a lab.
Image source: Getty Images.

So, first, why should you turn away from Moderna right now? The biotech offers a promising recovery story and potentially a long-term growth story too, but it involves some risk: It still must reach certain goals, such as cash breakeven in 2028 or the launch of new products over the next few years. This means Moderna may not be the best choice for cautious investors.

But, Vertex Pharmaceuticals (NASDAQ: VRTX) is a biotech player that’s suitable for both cautious and aggressive investors right now. The company has a long track record of earnings growth thanks to its leadership in cystic fibrosis (CF) treatment — it’s No. 1 worldwide in this area. The company transformed the treatment of this disease with its CFTR modulators, which correct a faulty protein made by the CFTR gene.

Vertex’s latest CFTR modulators, Trikafta and Alyftrek, approved in 2019 and in 2024, respectively, treat nearly 95% of those with CF — and Vertex is working on a candidate to treat this remaining percentage of the CF population that can’t be helped by these drugs. Importantly, Vertex’s intellectual property protects its position in this market through the late part of the next decade.

Vertex’s CF drugs are bringing in billions of dollars in sales — for example, the company’s total revenue climbed 11% to more than $3 billion in the latest quarter — and this momentum is very likely to continue due to the strength of the CF products.

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