Wednesday, December 3, 2025

Novo Nordisk Just Signed a Key Drug Deal With Omeros. Is There Any Room Left for OMER Stock to Run?

Omeros (OMER) shares closed more than 150% higher on Oct. 15 after the biotechnology firm announced a licensing agreement with the Danish pharmaceutical giant Novo Nordisk (NVO).

The deal includes $340 million in upfront and near-term milestone payments, along with additional potential deployment and commercial milestones, plus tiered royalties on net sales.

In total, the transaction is worth up to $2.1 billion. At the time of writing, OMER stock is trading up more than 260% from its year-to-date low.

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The centerpiece of the announced agreement is zaltenibart, Omeros’ promising drug candidate for treating paroxysmal nocturnal hemoglobinuria, a rare blood disorder.

Novo plans on initiating a global Phase 3 program for zaltenibart once the deal closes by the end of 2025, demonstrating confidence in the drug’s potential as a best-in-class treatment approach.

A sharp increase in the OMER share price following the news reflects market confidence in the transaction and potential synergies between the two healthcare companies.

For Omeros, the upfront and near-term milestone payments mean immediate liquidity while tiered royalties and the overall deal valuation of $2.1 billion offer long-term upside.

Teaming up with Novo Nordisk offer OMER access to the behemoth’s extensive development and commercialization expertise, substantially improving zaltenibart’s potential across all indications.

A strengthened balance sheet positions the company favorably for future research and development, while the retention of certain rights to preclinical MASP-3 programs maintains additional value.

The Novo Nordisk deal enhances Omeros’ risk profile and growth prospects, potentially driving institutional capital into the biotech stock.

Options data currently suggests continued upside momentum to over $16 through the end of 2025 since the macroeconomic backdrop, easing interest rates and subsequently improving risk appetite, could also drive OMER stock higher from here.

Note that Wall Street had an exceptionally bullish stance on Omeros stock even without the Novo Nordisk agreement.

Heading into Wednesday, analysts had a consensus “Moderate Buy” rating on OMER shares with a mean target of about $22 indicating potential upside of another 100% from current levels.

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AI-generated content may be incorrect.
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This article was generated with the support of AI and reviewed by an editor. On the date of publication, the editor did not have (either directly or indirectly) positions in any of the securities mentioned in this article. All information and data in this article is solely for informational purposes. This article was originally published on Barchart.com

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