Which ETF Is the Better Buy for Investors in 2026?

The State Street Health Care Select Sector SPDR ETF (NYSEMKT:XLV) provides concentrated exposure to blue-chip healthcare giants, while the Vanguard Health Care ETF (NYSEMKT:VHT) offers a wider reach including small- and mid-cap companies. Healthcare remains a cornerstone of the American economy, and these two funds offer distinct ways to own it. While both seek to…


Which ETF Is the Better Buy for Investors in 2026?

The State Street Health Care Select Sector SPDR ETF (NYSEMKT:XLV) provides concentrated exposure to blue-chip healthcare giants, while the Vanguard Health Care ETF (NYSEMKT:VHT) offers a wider reach including small- and mid-cap companies.

Healthcare remains a cornerstone of the American economy, and these two funds offer distinct ways to own it. While both seek to track the performance of the medical and wellness industries, the degree of diversification varies significantly between the two portfolios, impacting concentration risk and market-cap exposure.

Snapshot (cost & size)

Beta measures price volatility relative to the S&P 500; beta is calculated from monthly returns over the available fund history (up to five years). The 1-yr return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield as of the close of trading on August 8.

The State Street fund is nominally more affordable with an expense ratio of 0.08%, just one basis point below the Vanguard fund’s 0.09%. Both funds currently offer an identical 1.5% dividend yield, making management costs a primary differentiator.

Performance & risk comparison

What’s inside

The Vanguard Health Care ETF tracks a broad index of medical companies, providing exposure to 423 holdings. This breadth includes many small- and mid-sized firms that its competitor ignores, and its largest positions include Eli Lilly & Co (NYSE:LLY) at 14.2%, Johnson & Johnson (NYSE:JNJ) at 8.9%, and AbbVie Inc (NYSE:ABBV) at 6.6%. Launched in 2004, it is heavily weighted toward healthcare at 99%, with slight exposure to financial services, technology, and industrials. The Vanguard Health Care ETF has paid $4.72 per share over the trailing 12 months, which on its recent $309.02 share price works out to a 1.5% yield.

The State Street Health Care Select Sector SPDR ETF focuses strictly on the healthcare names within the S&P 500, holding only 60 stocks. Its largest positions include Eli Lilly & Co at 15.5%, Johnson & Johnson at 10.5%, and AbbVie Inc at 7.8%. Launched in 1998, it is currently all allocated to healthcare although at times it will have small amounts in related technology businesses. The State Street Health Care Select Sector SPDR ETF has paid $2.53 per share over the trailing 12 months, which on its recent $164.45 share price works out to a 1.5% yield.

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